Abstracts
International Journal of Clinical Nutrition (IJCN) ISSN (India) 0971-9210, Url: https://ijcnworld.com/
A publication of the International College of Nutrition,
2010; Vol 10(1): 1-25
1.THE ROLE OF BEE PRODUCTS IN THE PREVENTION AND TREATMENT OF CARDIOMETABOLIC DISORDERS.CLINICO-PHARMACOLOGICAL STUDY.
Teodora Handjieva-Darlenska(1), Aneliya Kuzeva(2), Svetoslav Handjiev(3)1,2Medical University of Sofia, 3Bulgaria; Bulgrian Association of the Study of Obesity and Related Diseases (BASORD);
Correspondence:
Dr Svetoslav Handjiev,MD, PhD 1233 Sofia, Krousha Planina Str.
Bulgaria; tel 00359888566420, Email: <svhandjiev@gmail.com>
Abstract
Epidemiological studies indicate that cardiometabolic diseases (CMDs) have become a worldwide cause of morbidity and mortality, despite tremendous advancement in drud therapy. Diet and lifestyle changes are important in the pathogenesis and prevention of these problems. Honey bee (Apis mellifera L.) is known to collect propolis which is a sticky, resinous material from various plants and mix with wax and other secretions. There are several biological functions of propolis that have been reported including cytotoxic, antimicrobial, antiviral, free radical scavenging, anti-inflammatory, local anesthetic, hepatoprotective, antitumor, and immune system stimulating. Propolis is widely used in popular medicine and apitherapy, with extensive use in food and beverages to improve health and prevent diseases in Estern European countries
Bee products are rich in flavonoids which are potential antioxidants. These antioxidants have been demonstrated to be protective against cardiometabolic disease (CMDs), cardiovascular disease, obesity, metabolic syndrome and type 2 diabetes.The aim of the article is to clarify the effect of bee products on the parameters of metabolism and the cardiovascular system in the management of obesity and metabolic disorders based on our studies in the past years. The studies showed the effects of bee producs (propolis, multiflower honey, royal jelly and bee pollen) in the management of metabolic disorders by decreasing body mass index, obesity, blood pressures and blood lipoproteins. The results indicate that bee products can be administered in the treatment of obesity and early prevention of atherosclerosis and heart disease.
Key words: apidietetics, propolis, multiflower honey, royal jelly, bee pollen, metabolic disorders, obesity.
How to cite:. Darlenska TH, Kuzeva A, Handjiev S. The role of bee products in the prevention and treatment of cardiometabolic disorders. Int J Clin Nutrition 2010; 10: 1-5.
Sergey Chibisov, mukta Singh, Ram B Singh (3),,Rie Horiuchi,,Toru Takahashi. Functional food security for prevention of obesity and metabolic syndrome. In RB Singh, Toru Takahashi, RR Watson, Functional Food Security in Global Health. Elsevier, Chapter 8, Cambridge,USA 2018, 145-154.
2.NUTRITIONAL PREVENTION OF OBESITY AND METABOLIC SYNDROME.
Mukta Singh (1), Sergey Chibisov (2), Ram B Singh (3),Ghazi Halabi (4),Rie Horiuchi (5),Toru Takahashi (6), 2Department of General Pathology and Pathological Physiology RUDN University, Moscow, Russia; 3Halberg Hospital and Research Institute, Moradabad, India;4Medical 2000 Hospital, Choueifat, Labanon; 5Mukogawa Women’s University, Nishinomiya city, 6Graduate School of Human Environmental Medicine, Fukuoka, Japan.
Correspondence
Dr. Sergey Chibisov, MD, PhD
Department of General Pathology and Pathological Physiology RUDN University,
Moscow, Russia, Email: <kalcna@mail.ru> , rbs@tsimtsoum.net, Tel. +7 926 47124 28
Abstract
The world is still ignorant about the role of functional food security characterized by diversity and adequacy of nutrients that may have been beneficial and abundant in the Paleolithic diet 40,000 years ago because of food diversity. Therefore, the increased prevalence of metabolic syndrome and the resultant type 2 diabetes, hypertension and heart disease throughout the world, are closely linked to food security via westernized dietary patterns, physical inactivity, and rapid increase in the rate of obesity. Further, evidence from prospective observational studies and clinical trials has converged to support the importance of individual nutrients, foods, and dietary patterns in the prevention and management of obesity and metabolic syndrome. The quality of dietary fats and carbohydrates consumed is more crucial than the quantity of these nutrients. Diets rich in whole grains, fruits, vegetables, legumes, nuts, moderate in alcohol consumption, and lower in refined grains, red/processed meats, and sugar-sweetened beverages have demonstrated to reduce risk of obesity and metabolic syndrome. Several healthful dietary patterns emphasizing the overall diet quality can be adapted to appropriate personal and cultural food preferences and calorie needs for weight control and management. Considerable progress has been made in developing and implementing evidence-based nutrition recommendations in developed countries, however, concerted global efforts and policies are warranted to alleviate regional disparities. There is substantial evidence that increased intake of functional foods can bring about a significant decline in the epidemic of obesity and metabolic syndrome, resulting in to health promotion. We therefore propose that functional food security in conjunction with regular physical activity, can maintain the normal physiology and metabolism of the community, resulting in to decrease in the epidemic of obesity and improvement in world health.
Key Words. Foods, dietary patterns, western diet, prudent diet.
How to cite: Singh M, Chibisov S, Singh RB, Halabi G, Horiuchi R, Takahashi T. Nutritional prevention of obesity and metabolic syndrome. In J Clin Nutrition 2010; 10: 6-10.
- NUTRITIONAL PREVENTION OF CARDIOVASCULAR DISEASES.
Shantanu Singhal (1), Jan Fedacko (2),Dominik Pella (3), Krasimira Hristova (4),Meenakshi Jain(5), Ghazi Halabi(6) 1Halberg Hospital and Research Institute, Moradbad, India; 2,3 PJ safari University, Kosice, Slovakia; 4University National Heart Hospital, Sofia, Bulgaria; 5Max Hospital, Delhi, India; Halberg Cardiac Center, Aley, Labonon.
Corresponding Author:
Prof Dr Jan Fedacko, MD, PhD, FICC,
Department of Medicine, Faculty of Medicine,
PJ Safaric University, Kosice, Slovakia. janfedacko@hotmail.com; Tel: 421 911-315-924
Abstract
It is possible that food diversity was the major factor causing adequacy of nutrients in the Paleolithic diet 40,000 years ago. Increased demand for food security has made the world blind about the utility and necessity of functional food security characterized with food diversity and adequacy of nutrients. The increased prevalence of cardiovascular diseases (CVDs) and type2 diabetes throughout the world are closely linked to food security via westernized dietary patterns, physical inactivity, and rapid increase in the rates of obesity. The World Heart Federation, World Health Organization and the International College of Cardiology are working hard to find out strategy to bring down the death rates due to CVDs, at least 25% by 2025.There is substantial evidence that increased intake of functional foods can bring about a significant decline in the epidemic of CVDs and type 2 diabetes, resulting in health promotion. The traditional Mediterranean-style diet, characterized by high consumption of functional foods (vegetables, legumes, whole grains, fruits, nuts, and olive oil), moderate consumption of fish and wine, and low consumption of red and processed meat and whole-fat dairy products, is widely recognized as a healthy dietary pattern, rich in functional foods, which is similar to Paleolithic diet. It is possible that functional food security by providing 400g/day of fruits (150g), vegetables (200g) and nuts (50-60g) and another 400g/day of pulses and whole grains, in conjunction with 30-50g of a blend of olive oil+ canola oil and rice bran oil as well as regular physical activity, can maintain the normal physiology and metabolism of our bodies, resulting into decline in CVDs.
Key Words: Foods, dietary patterns, western diet, prudent diet.
How to cite: Shantanu Singhal (1), Jan Fedacko (2),Dominik Pella (3), Krasimira Hristova (4),Meenakshi Jain(5), Ghazi Halabi(6) nutritional prevention of cardiovascular diseases. Int J Clin Nutrition 2010; 10: 11-15.
- FUNCTIONAL FOOD SECURITY FOR PREVENTION OF DIABETES MELLITUS..
Anuj Maheshwari (1),Banshi Saboo (2), Shashank Joshi (3), Narsingh Verma (4), Viola Vargova (5), Dominik Pella (5),Daniel Pella (5) 1BBD, CODS, BBD University, Lucknow, 2Dia-Care and Hormone Institute, Ahamadabad, 3Leelawati Hospital, Mumbai; 4KG Medical University, Lucknow, India; 5Faculty of Medicine, PJ Safaric University, Kosice, Slovakia
Correspondence
Prof. Dr Anuj Maheshwari,MD, FRCP(London) Department of Medicine,BBD, CODS, BBD University, Lucknow (UP), India,dranujm@gmail.com,rbs@tsimtsoum.net, Tel.91 9839133984
Abstract
The epidemic of diabetes mellitus has grown in parallel with the worldwide rise in obesity which is a potential risk factor of type 2 diabetes. Emergence of fast food restaurants exponentially and globally in recent decades appears to be important factor. This increased availability of fast foods has contributed to unhealthful diets with high calorie content; large portion sizes; and large amounts of processed meat, highly refined carbohydrates, sugary beverages, and unhealthy fats; trans fat, saturated fat and omega-6 fat with low omega-3 and monounsaturated fat. There has been a decreased consumption of vegetables, whole grains and nuts causing imbalance in food consumption pattern resulting in to obesity and diabetes. Fuctional food security by increased availability of vegetables, whole, grains and nuts, and a blend of oils containing olive oil and mustard oil may be useful in the prevention of diabetes.
Key Words. Vegetables, nuts, fruits, Mediterranean diet.
How to cite: Anuj Maheshwari (1),Banshi Saboo (2), Shashank Joshi (3), Narsingh Verma (4), Viola Vargova (5), Dominik Pella (5),Daniel Pella (5) Functional food security for prevention of diabetes mellitus. Int J clin Nutrition 2010; 10: 16-20.
- EFFECT OF GLYCEMIC INDEX OF FOODS ON BIOMARKERS OF VASCULAR DISEASE. Mahmood Moshiri (1), Adrian Isaza (2), Kiarash Moshiri (3),Aminat Magamedova (4). 1,3International College of Nutrition, Thornhill, Canada; 2Everglade University, Tampa, USA; Lomonosov Moscow State University, Moscow, Russia
Correspondence
Dr Amonat Magamedova, PhD
Lomonosov Moscow State University,
Moscow, Russia, Аминат Mагомедова <amgerma@gmail.com>
Abstract
In a randomized, clinical trial, it has been hypothesized that a low compared with a high glycemic index, especially of a high-carbohydrate diet, would cause modest though potentially important improvements in insulin sensitivity and cardiovascular disease (CVD) risk, but the findings were opposite. The study found out the short term adverse effects of high glycemic index foods, without taking healthful foods. Oxidation of LDL and HDL are also important determinants of atherothrombosis which need further evidence. The four diets were: (1) a high-glycaemic index (65% on the glucose scale), high-carbohydrate diet (58%); (2) a low-glycaemic index (40%), high-carbohydrate diet; (3) a high-glycaemic index, low-carbohydrate diet (40%); and (4) a low-glycaemic index, low-carbohydrate diet. Each diet was based on a healthful Dietary Approaches to Stop Hypertension (DASH)-type diet, which is rich in fruits, vegetables, and low-fat dairy foods, and low in saturated and total fat. It seems that they should have also included a sub group not taking healthful DASH type diet. The OmniCarb Randomized Clinical Trial showed that adding DASH diet can modulate the adverse effects of high glycemic index on coronary risk factors and insulin resistance. This interesting finding was that adding polyphenolics or fruit juice in the infant milk may provide super infant milk for future trials. It is well known that increased intake of rapidly absorbed ready prepared foods with high glycemic index cause hyperglycemia, increase in superoxide anion, free fatty acids and pro-inflammatory cytokines causing endothelial dysfunction which were not measured in this study. The high glycemic index foods may also increase sympathetic activity and lower parasympathetic activity causing increase in catecholamines and cortisol with a decrease in acetylecholine which may have adverse effects. In an experimental study, Western diet increased the heart rate, which was attenuated by adrenergic blockade suggesting an increased sympathetic activity. Reduced response to muscarinic blockade suggested a decreased parasympathetic activity fitting with sympathetic activation.
Key words. Rapidly absorbed food, refined CHO, nutrition, diet.
How to cite:. Mahmood Moshiri (1), Adrian Isaza (2), Kiarash Moshiri (3),Aminat Magamedova (4). Effect of glycemic index of foods on biomarkers of vascular disease. Int J Clin Nutrition 2010; 10: 21-25.